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However, substantial heterogeneity among studies was observed, likely attributable to differences in dosage, baseline B12 status, and population characteristics

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found that circ_0000808 was upregulated in NSCLC cells, where it enhanced the expression of the Gln transporter SLC1A5 by interacting with miR1827, thereby promoting Gln metabolism and facilitating the progression of NSCLC (56)

Mechanism-based caution in users with active cancer is the dominant community pattern