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Splicing occurs through XBP1 mRNA to the translation of sXBP1 protein, which is a transcription factor that induces genes involved in chaperoning proteins and degrades misfolded proteins in ER, thus triggering inflammatory reaction and promoting cell apoptosis mediated by apoptosis ASK1 and JNK [99, 102]
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Stress, poor sleep, hormonal imbalances, and the standard American diet can disrupt metabolic health at any age
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