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74 In one randomized, placebo-controlled, crossover trial that included 24 healthy participants aged 55 years and older who had no major sleep issues, 5 mg melatonin 30 minutes before bedtime in controlled experimental conditions increased sleep efficiency, mainly by increasing stage 2 NREM sleep and slightly shortening awakenings
10.1245/s10434-014-4276-3 85 PetrekJ
A recent example is the SELECT trial finding that Ozempic (semaglutide) reduced cardiovascular events by 20% in overweight or obese adults with established heart disease and without diabetes
For a deeper comparison, explore our guide on Semaglutide vs
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