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It belongs to the pharmacological class of medications known as glucagon-like peptide-1 receptor agonists (GLP-1 RAs), which are designed to mimic the action of the endogenous incretin hormone GLP-1
These findings are consistent with indirect comparisons from network meta-analyses and systematic reviews, which generally report superior weight-loss outcomes with tirzepatide compared with GLP-1 receptor agonists alone
The National Weight Control Registry, which tracks individuals who have successfully maintained significant weight loss, reports that successful maintainers typically consume a relatively low-calorie, low-fat diet with consistent meal patterns
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Food remains in the stomach for a longer period, which helps prolong satiety and reduces the frequency of eating
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