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One notable pilot study published in the European Journal of Clinical Nutrition followed healthy adults taking liposomal glutathione daily

Although ANXA1 was reported to be involved primarily in inflammation processes, it also has pro-apoptotic functions, which include activation of p38 and JNK signaling pathways, 35 co-localization with phosphatidylserine on the outer plasma membrane leaflet, 36 and activation of caspase-3

Decreased levels may suggest adrenal hyperplasia, Addisons disease, hypopituitarism, or hypothyroidism