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Compared to NSAIDs: No gastrointestinal toxicity No cardiac risks No kidney damage risk No drug interactions Actively promotes healing rather than masking symptoms Compared to corticosteroids: No immunosuppression No bone density loss No endocrine disruption No adrenal suppression Promotes healing rather than suppressing inflammation Compared to other peptides: Similar or better safety profile Minimal side effects No hormonal disruption Well tolerated across populations Regulatory and Ethical Considerations Researchers should be aware of the regulatory status
Lancet 404 , 949961 (2024)
Health Canada authorized two manufacturers within days of each other: Dr
GLP-1R contributes to microglial activation in the TNC in NTG-induced CM mice We have indicated that chronic NTG stimulation induces an increase in the number and activity of microglia in the TNC
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