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doi: 10.1016/j.exer.2006.07.014
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Symptoms may include fatigue, weakness, memory problems, difficulty concentrating, mood changes, numbness or tingling in the hands and feet, and difficulty maintaining balance
10.3390/cells9071710 266
The general principle these definitions reflect is a pharmacokinetic property rather than a dosing instruction: with a half-life of roughly one week, exposure declines gradually rather than abruptly across a shifted or missed interval
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