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Unfortunately, these immune cells arent successful at killing the infection

Pathogenic variants of LRRK2 are the most common cause of familial PD and also account for ~1% of sporadic PD 16

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However, certain symptoms require prompt evaluation: Trouble breathing, noisy breathing, or choking sensations Inability to swallow liquids or solids Rapidly enlarging neck mass, visible swelling, or redness Unexplained weight loss, persistent pain, or bleeding Hoarseness lasting more than two weeks How Clinicians Evaluate a Lump-in-the-Throat Sensation Evaluation begins with a careful history and physical exam

Some patients may also experience fatigue or mild stomach discomfort, especially during the first few weeks of treatment