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Prx1 hyperoxidation protects matrix glutathione from H 2 O 2 induced oxidation Given that Prx1 appears to efficiently catalyze the transfer of oxidative equivalents from H 2 O 2 to glutathione, we next asked about the consequences of acute H 2 O 2 challenges for the mitochondrial matrix glutathione pool

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And the nervous and immune systems are protected from collateral damage throughout (neuroprotection)

Ma L, Chen Y, Gong Q, Cheng Z, Ran C, Liu K, et al

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