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Unlike supplements, who would need to pass through the digestive system
The preference for metformin as the initial agent is based on its durable efficacy in lowering A1C, absence of risk for hypoglycemia or weight gain, relatively mild side-effect profile, longterm safety track record, and affordability
Why Personalization Matters in Dosing Weight loss is not a one-size-fits-all process
Health plans should work alongside PBMs and GLP-1 manufacturers to drive down costs, unlock rebates to further mitigate cost challenges and enhance drug commercialization (e.g., joint production partnerships, marketing partnerships)
Novo Nordisk (press release)
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