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Journal of Investigative Dermatology, Volume 113, Issue 3, 1999, Pages 364-368
Functional analysis of the role of glutathione peroxidase (GPx) in the ROS signaling pathway, hyphal branching and the regulation of ganoderic acid biosynthesis in Ganoderma lucidum
Use of this model allows us to observe MYCmediated metabolic reprogramming in the native tumor environment 23
However, selective NaV1.7 inhibitors have repeatedly failed in the clinic, and recent studies across multiple programs point to on-target autonomic and cardiovascular liabilities
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