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People switching between different GLP-1 medications, such as those switching from semaglutide to tirzepatide , should know that side effect profiles differ between these drugs even though they target similar pathways
This may have resulted from the timing of the study relative to the COVID-19 pandemic (SURMOUNT-1 and STEP during, ONeil and SCALE Obesity and Prediabetes prior), which may have impacted the reporting of safety events
The authors appreciate the constructive feedback provided by Dr
Key highlights As of 2025, there is no FDA-approved generic semaglutide in the United States, but alternatives and cost-saving options exist
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