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PubMed: 33965067 Phase 2a: Weight Loss Efficacy Study (NCT03224429) Study Title: "Efficacy and Safety of Cagrilintide for Weight Management in Adults With Overweight or Obesity" Status: Completed Phase: Phase 2a Enrollment: 706 participants Study Period: 2018-2020 Location: Multi-country (US, Europe) Design: Randomized, double-blind, placebo-controlled Duration: 26 weeks Intervention: Cagrilintide 0.6/1.2/2.4/4.5 mg weekly Population: BMI 30 or 27 with comorbidity, no diabetes Key Results (26 Weeks): Mean Weight Loss: 10.8% at 4.5 mg (highest dose) 8.6% at 2.4 mg 6.0% at 1.2 mg 4.3% at 0.6 mg 3.0% with placebo 10% Weight Loss: 51% (4.5 mg) vs

The test subjects administered the highest dose of Dihexa spent the most amount of time in the target quadrant compared to the groups of animals treated with scopolamine alone

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Chemical Makeup Other Known Titles BPC-157: C 62 H 98 N 16 O 22 TB-500: C 212 H 350 N 56 O 78 S GHK-Cu: C 14 H 23 CuN 6 O 4 Molecular Weight: BPC-157: 5 g/mol TB-500: 4963 g/mol GHK-Cu: 38 g/mol Molecular Formula: BPC-157: Body Protection Compound-157 TB-500: Synthetic Thymosin Beta-4 GHK-Cu: glycyl-L-histidyl-L-lysine-copper 2+ Research and Clinical Studies Anti-inflammatory Signaling Research on BPC-157 & TB-500 & GHK-Cu All three peptides appear to play some potentially complementary and partially overlapping roles in inflammatory signaling inside and in between cells