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Wegovy received NICE approval in 2023 for weight management in adults with a BMI 35 kg/m (or 32.5 kg/m for people from South Asian, Chinese, other Asian, Middle Eastern, Black African, or African-Caribbean backgrounds) with at least one weight-related comorbidity

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The number of smokers and non-smokers (16.5% vs 42.6% in the oral and 18.1% vs 32.7% in the subcutaneous semaglutide group, respectively) was similar between the two groups

These are administered by subcutaneous injection (semaglutide once weekly