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348 Recently, Olivia Majer team also identified another novel regulatory mechanism that restricts TLR9 activation to endosomal compartments

Actin is a structural protein that drives cell movement, and TB-500 binds to actin monomers in a way that supports cell migration into damaged tissue

These stressors create free radicals

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These findings suggest that cell pro-inflammatory factors such as IL-1, IL-6, and TNF- are key immunological hubs through which the oral cavity microbiota affects intestinal homeostasis and drives systemic inflammation and disease progression