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With the rapid weight reduction caused by GLP-1 agonists, 25 to 40 % of the loss is lean mass (muscle tissue)
In contrast, for HOMA-IR, LC n3-PUFA supplementation was associated with a modest but statistically significant reduction (SMD: 0.42
In CAR, intracellular concentrations of carnitine and BB in PBMC progressively increased until the end of the study, suggesting an accumulation in PBMC over time
Among these, the STEP (Semaglutide Treatment Effect in People with obesity) trials stand out as a cornerstone in understanding its effectiveness
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