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observed concentrationtime profiles, using single and multiple dosing regimens of clinical data from the testing dataset ( max ), area under the curve from 0 to infinity time (AUC 0-inf ), half-life (T 1/2 ), the time to reach peak concentration (T max ), and clearance over bioavailability (CL/F), were compared between predictions and observations using the fold error and the average fold error (AFE), calculated according to Eq
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More often, it is a sign that your digestive system is struggling with the slowed pace of gastric emptying, leading to constipation and irritation
