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These properties made GLP-1 receptor agonists a breakthrough class of medications for type 2 diabetes and obesity
Step 5: Label and store Write the following on the vial or on a label you attach to it: the reconstitution date, the concentration (mg/mL), and the discard-by date (typically 28-60 days after reconstitution depending on the medication)
For someone starting at 0.25 mg and planning to escalate to 1.0 mg: At 2.5 mg/mL: 0.25 mg = 10 units, 1.0 mg = 40 units (ideal range) At 5 mg/mL: 0.25 mg = 5 units, 1.0 mg = 20 units (workable but tight at low end) The 2.5 mg/mL option keeps all doses in a comfortable measurement range
For NMR measurements, the samples were re-suspended in 200 L NMR buffer (50 mM sodium phosphate buffer in D 2 O at pH 7.2 with 0.1 mM DSS (4,4-dimethyl-4-silapentane-1-sulfonic acid) for referencing)
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