Many first-time users describe a burst of energy and focus in the first week that they mistake for the appetite suppression itself
These typically resolve within 8 to 24 hours but can lead to clinically significant complications, including dehydration, acute kidney injury, and electrolyte abnormalities
Many people first notice softer contours around the cheeks, fine lines that linger longer than they used to, or a loss of fullness that makes the face look more tired
Before you scoop, check out the Quality Concerns section of our Protein Powders, Shakes, and Meal Replacements Review, which includes our Top Picks for protein
And concern about continued access rises steadily with cost: Among people paying $500 to $1,000 per month, more than 1 in 3 say they are very concerned about losing access, compared with 15% of those whose medication is fully covered