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What Is Retatrutide Retatrutide is a synthetic peptide developed by Eli Lilly that produced the largest weight-loss results ever recorded in a Phase 2 obesity trial an average of 24.2% body weight reduction at the highest dose over 48 weeks
Yanovski JA, Krakoff J, Salaita CG, McDuffie JR, Kozlosky M, Sebring NG, et al
[178] [179] In March 2026, Eli Lilly announced a drug discovery deal with InSilico for an estimated value of $2.75 billion
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