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PMID 23746776
Singh et al, 2021), Genes common among published target sets include those related to redox biology (i.e., GCLC , SLC7A11 , TXN ) and the pentose-phosphate pathway (PPP, i.e., PGD , TALDO1 ), in addition to many NADP-dependent metabolic enzymes (i.e., AKR1C1 , AKR1B10 , and CYP4F11 )
Cholesterol is necessary since it helps our body to produce hormones that, consecutively, promotes a better digestion of food and also vitamin D
As such, while short-term, targeted use appears beneficial, further studies are needed to evaluate whether prolonged application maintains its ergogenic effects or if periodic cycling of supplementation is advisable to prevent plateauing of performance benefits
Accordingly, strategies to enhance the metabolism or efflux of lipids within neurons and glia have emerged as a promising therapeutic avenue in AD (Blanchard et al., 2022
