On September 25, 2025, Eli Lilly announced that it was halting a phase 2b trial of its candidate agent, bimagrumab, in combination with tirzepatide in people with obesity and type 2 diabetes for strategic business reasons, but it is continuing another phase 2 trial of the agent in people with overweight or obesity who do not have diabetes
Retatrutide acts on three metabolic receptors at once GLP-1, GIP and glucagon (a 'triple agonist')
However, there are individual studies for each medication showing their efficacy and researchers are closely examining their results in various settings
This study was supported by the NIHR Cambridge Biomedical Research Centre (BRC-1215-20014)
If you're a good candidate for treatment, your provider prescribes Tirzepatide, which is sourced from our partner FDA-registered compounding pharmacies