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Note that the senior author is Wright, the principal investigator of the Harding laboratory

The prevalence of vitamin B12 deficiency is particularly elevated among patients with T2D, with studies demonstrating that up to 64% of those with DPN exhibit altered (low or borderline) vitamin B12 levels compared with only 17% of patients without neuropathy

Latin America and the Middle East and Africa collectively accounted for roughly 10.5% and 6.1% of the global market in 2025, respectively, with growth in both regions expected to accelerate as healthcare infrastructure improves, income levels rise, and awareness of advanced aging therapies expands among specialist physician communities