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These observations have contributed to ongoing research interest in the compounds potential interactions with vascular endothelial growth factor pathways

DOI: 10.1371/journal.pone.0085637 49

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Treatment with tesamorelin resulted in an increase from baseline in mean lean body mass of 1.3 kg in Study 1 and of 1.2 kg in Study 2, respectively (compared with a decrease of 0.2 kg in Study 1 and of 0.03 kg in Study 2, respectively, in patients receiving placebo)