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Essential Monitoring and Patient Counseling: If combination therapy is pursued, providers should ensure: Close monitoring for gastrointestinal tolerability Vitamin supplementation (multivitamin with fat-soluble vitamins taken 2 hours from orlistat) Clear instructions on timing (orlistat with fat-containing meals, skip if meal is skipped or fat-free

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The approved dose of Wegovy is 2.4 mg, so doses of 1.7mg should be flagged for evaluation

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