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Oral delivery places the peptide in direct contact with the gastrointestinal mucosa, allowing localized action on the tissue that needs repair
This permitted a comprehensive and highly sensitive molecular comparison between hearts exposed to oral semaglutide therapy, and those that underwent ischemia induction alone
They are FDA-approved for obesity and increasingly used for other inflammatory conditions
Liraglutide directly protects cardiomyocytes against reperfusion injury possibly via modulation of intracellular calcium homeostasis
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