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A search on PubMed returns many papers on rodents and cell models, and reviews on PubMed Central describe it as a possible therapy rather than a proven one

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Boosting metabolism The glucagon component of retatrutide helps increase energy expenditure, potentially leading to greater fat loss compared to single or dual-receptor agonists

This association is driven by complex biological mechanisms, including chronic inflammation, insulin resistance, hormonal dysregulation, and immune system alterations that can contribute to tumor development and progression

doi:10.1210/clinem/dgab058