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Even if fragments survive the stomach, the small intestine adds more proteolytic enzymes: trypsin, chymotrypsin, elastase, and carboxypeptidases
Implications Amylin is centrally implicated in metabolic disease: dysregulated synthesis, impaired pro-IAPP processing and aggregation of amylin into islet amyloid are associated with -cell dysfunction and the progressive loss of -cell mass in type 2 diabetes (T2D)
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Not only is it important to know all the beneficial effects, but it also is important to know the potential negative effects, so patients can be counseled properly. The next steps would be to design a study to see the mechanism for improvement in cardiovascular health, he added
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