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Results vary and carry potential risks
Chemically, these compounds are not related to naturally occurring cannabinoids, but their actions in the body create a high that resembles marijuana in some ways
The fast reduction of GPx3 expression following selenium depletion places GPx3 in the lower ranks of the selenium hierarchy (Brigelius-Flohe, 1999)
As I said before PA is still thought to be the primary culprit here, other causes of B12 deficiency such as malabsorption caused by metformin, H2 blockers, PPIs, parasites, etc
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