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Bioactivities of berberine metabolites after transformation through CYP450 isoenzymes
Conclusion: Our study findings provide a comprehensive metabolomic knowledge base and other soluble biomarkers for a better understanding of the pathophysiology of LC and suggests sarcosine and serine supplementations might have potential therapeutic implications in LC patients
Most chemicals, either produced by the body or to which we are exposed through our diet and environment, first undergo phase I detoxification, which produces highly reactive and carcinogenic by-products
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