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The authors concluded that once-weekly tirzepatide induced superior glycaemic control compared with daily insulin degludec in adults with T2DM treated with metformin, with or without an SGLT2 inhibitor
Theres going to be an explosion in the sheer number of compounds Kumar has found he can design bias into GLP-1 analogues by simply alkylating or trifluoroalkylating the N -terminal amino acid using an alkyl halide
GLP-1 medications are also being studied for the treatment of other conditions, which could lead to expanded FDA-approved uses
The synthesis were conducted with microwave irradiation using the Liberty Blue TM microwave peptide synthesizer from CEM S.A.S
This review summarizes some of the clinical data on GLP-1 RA (Table 3), with some exciting results
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