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Various cytokines secreted by different cells within the TME can promote or inhibit ferroptosis, and the sensitivity of the TME to these cytokines also differs (10)

AKI was defined according to the Kidney Disease: Improving Global Outcomes (KDIGO) consensus serum creatinine criteria as either an increase in serum creatinine of 0.3 mg/dL (26.5 mol/L) within 48 hours or an increase to 1.5 times baseline within the preceding 7 days (29)

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