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It also decreases the amount of reactive oxygen species (ROS) and reduces oxidative stress, which can otherwise cause molecular and DNA damage

As previously introduced, the disruption of the TCA cycle in M1 macrophages leads to the accumulation of citrate

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As toxicologic pathologists sometimes experience difficulties in distinguishing the wide variety of liver lesions in the rodents for safety evaluation purposes, this document is a consensus of senior toxicologic pathologists regarding suggested nomenclature that should be used for specific lesions

" Sadly I don't know the answer to that as I'm not medically trained