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doi:10.1176/appi.ajp.2008.165.12.1614
H., Thougaard, A
Ferroptosis-related factors in the substantia nigra are associated with Parkinsons disease
The mouse lysyl oxidase-like 2 gene (mLOXL2) maps to chromosome 14 and is highly expressed in skin, lung and thymus
Its molecular target is nicotinamide N-methyltransferase (NNMT), a cytosolic S-adenosyl-L-methionine-dependent methyltransferase that converts nicotinamide to 1-methylnicotinamide, consuming SAM and releasing S-adenosylhomocysteine
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