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IV (weeks 156 to 190)
Mechanism of Action and Direct Metabolic Effects Semaglutide works by mimicking the naturally occurring GLP-1 hormone, which enhances glucose-dependent insulin secretion from pancreatic beta cells and suppresses inappropriate glucagon release
Koh ES, Han K, Nam YS, et al
How gut health triggers GLP-1: When your gut bacteria are happy and healthy, they send signals to increase GLP-1 production, which helps manage hunger and blood sugar
It is not FDA-approved itself, but the safety profile of semaglutide as a drug class is well-established
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