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Felker D, Lynn A, Wang S, Johnson DE
Taken together, the evidence suggests that class-wide disease modification in Parkinsons, at the compounds and doses tested so far, is unlikely, even if a responder subgroup may yet exist
(They studied participants who did not have diabetes because the disease introduces more confounding variables.) The team initially expected that individuals with the PAM variant would have lower GLP-1 levels, possibly because the hormone would be less stable without proper processing
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