Gao V, Suzuki A, Magistretti PJ, Lengacher S, Pollonini G, Steinman MQ, et al
A novel interaction of diethyldithiocarbamate with the glutathione/glutathione [PMID: 3019961] Laboratory literature summary: A novel interaction of diethyldithiocarbamate with the glutathione/glutathione peroxidase system
A 2021 phase 2 trial published in The New England Journal of Medicine showed semaglutide 2.4 mg achieved NASH resolution without worsening fibrosis in 59% of patients versus 17% on placebo (Newsome et al., NEJM 2021)
Cognitive function in obese individuals improves substantially with weight loss alone, but the direct central GLP-1R effects may contribute additional benefit beyond what weight reduction alone would predict
Gaucher C, Boudier A, Bonetti J, Clarot I, Leroy P, Parent M