Indirect comparisons using network meta-analysis suggest tirzepatide 15 mg produces approximately 5, 6 percentage points greater weight loss than semaglutide 2.4 mg, but trial populations differ in ways that complicate direct comparison
Ibrahim NAM, Mansour YSE, Sulieman A, Hussein HS
Relationships among smoking, oxidative stress, inflammation, macromolecular damage, and cancer
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The decision to continue, modify, or discontinue semaglutide should be made collaboratively, weighing the therapeutic benefits against tolerability concerns and individual patient circumstances