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Cyril Bowers at Tulane synthesized it in 1980 as a derivative of met-enkephalin opioid peptides not, interestingly, because he was trying to build a GH secretagogue
10.1038/ijo.2011.147 90 ShiraziR
GLP-1 RAs as an add-on showed a reduction in BMI compared to controls (mean difference 1.38 kg/m, low certainty evidence)
Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: a randomized controlled trial
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