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Intermittent PI3K inhibition reshapes the immune TME in PTEN-null prostate cancer, converts cold tumors to hot tumors, suppresses T regs while preserving CD8 + T-cell function, and maintains inflammatory states posttreatment
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Early findings around GLP-1s and addiction preclinical research suggest: Reduced drug-seeking behaviors in animal models involving opioids, nicotine, and stimulants Possible changes in reward sensitivity and reinforcement mechanisms Overlap between neural pathways involved in appetite regulation and substance use However, translating these findings to human populations has proven challenging
Cognitive effects of adjunctive N-acetyl cysteine in psychosis
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