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Clinical Manifestations of Vitamin B12 Deficiency Although the classic hematologic expression of vitamin B 12 deficiency is a megaloblastic macrocytic anemia characterized by an elevated mean corpuscular volume and mean corpuscular hemoglobin, and a peripheral smear containing macroovalocytes and hypersegmented neutrophils, up to 28 percent of affected patients may have a normal hemoglobin level, and up to 17 percent may have a normal mean corpuscular volume

As an essential vitamin that supports the health of your nerve cells and is vital for DNA synthesis and red blood cell production, B12 can be a game-changer, especially for those who do not get enough from their diet or have absorption issues

Spoiler alert: While we hate to be the bearer of bad news, as of yet, theres no magic solution

Its primary mechanism is VEGF upregulation, the growth of new blood vessels that supply oxygen and nutrients to injured tissue, alongside nitric oxide pathway modulation and fibroblast stimulation in tendon and ligament tissue

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