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[63] demonstrated that lyophilized L

Topical Administration (Most Common) The most widely used approach is topical application via DMSO (dimethyl sulfoxide): Dissolve 3-5mg Dihexa in a few drops of DMSO Apply to forearm skin (DMSO acts as a carrier to drive the peptide through the skin) DMSO concentration: ~20-30% in the solution Pros: Effective absorption, avoids injection Cons: DMSO has a strong garlic-like odor that can transfer to breath/skin Starting Dose Begin at 1-3mg topically to assess response Work up to 3-5mg if tolerating well Cycling Protocol Dihexa appears to have lasting effects that persist after stopping likely due to synaptogenesis (new connections don't disappear when you stop)

MOTS-c runs 20 days on, 4 months off

PT-141 (bremelanotide) is an FDA-approved peptide, sold under the brand name Vyleesi, used to treat low sexual desire in premenopausal women

Johns Hospital in Springfield, Ill