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Once anesthetized, the right knee joints of the animals were shaved, sterilized, and subjected to an intra-articular injection of collagenase type II

Over time, as the body adjusts, the schedule can be adapted based on response and laboratory results if needed

Possible temporary reactions include mild soreness at the injection site, nausea, headache, or dizziness for a day or two, and occasional minor bruising

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Numerous patients exhibit a deficiency in vitamin B12 due to factors such as stress, poor dietary habits, subpar digestion, or the depletion of this crucial nutrient by certain medications