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Mitochondria produce ROS during adenosine triphosphate (ATP) generation, with some electrons leaking from the electron transport chain (ETC), which subsequently leads to superoxide anion production [66]
Additionally, the significant weight loss achieved with GLP-1 receptor agonists leads to changes in body composition, fluid distribution, and metabolic rate, all of which can influence cardiovascular hemodynamics
The results showed that rats treated with DSIP recovered motor skills faster than untreated rats, even though the size of the brain damage wasnt significantly reduced
Nov 5 2022;21(1):232