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Hence, it is a significant target of small-molecule drugs for signaling modulation (Fig
Injections should be administered following clinical assessment, and long-term or repeated use should be medically guided
Cancer Res 50(23):7537-43, 1990
Due to the decrease in GH secretion, the secretion of IGF-1, which is driven by GH release, was also drastically reduced
This supercomplex in turn is thought to be activated by amino acids transported from the lysosomal lumen by transmembrane proteins, which in this way act as amino-acid sensors
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