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Pharmacological agents such as ergothioneine acid reduce the SSG of NF-B-dependent Wnt5a-sFlt1, improving post-MI outcomes by preserving GRX1 activity and myocardial integrity (84)
Nrf2 overexpression starts out playing a protective role in cancer, but ultimately encourages disease progression and metastasis, while mutations in Keap1 have been linked to a poor prognosis in individuals with advanced NSCLC receiving treatment [10]
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5.8 Evidence Strength Overview This table reflects current knowledge not speculation
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