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Side effects included nausea (31% of patients), diarrhea (23%) and vomiting (12.2%) [26]
Similarly, in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced PD mouse model, GLP-1 analogues were reported to protect the brain from MPTP-induced pathological effects, such as movement disorders, increased levels of -synuclein, chronic inflammation in the brain, loss of dopaminergic neurons, oxidative stress, and expression of growth factors (65)
It is important to note that most side effects are mild, transient, and resolve with continued use or dosage adjustment
elegans and increases muscle function in rodents