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the ISRCTN registry and ClinicalTrials.gov are also useful for searching registered studies Discuss currently approved options your doctor can explain whether semaglutide, tirzepatide, or other licensed treatments are appropriate for your circumstances Raise concerns about online purchases if you have already sourced or are considering sourcing unregulated peptides, your doctor can advise on the risks without judgement, and can help you report any adverse effects via the MHRA Yellow Card scheme Private weight management clinics, including those staffed by registered endocrinologists or bariatric physicians, may also offer access to the latest approved treatments and can sometimes facilitate referrals to clinical trials

J Anal Sci Technol 10, 35.CrossRefGoogle Scholar Hou, Y, Michiels, J, Kerschaver, CV, et al

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It's important to note that semaglutide is not recommended for patients with severe gastrointestinal disease, including severe gastroparesis, as these conditions have not been studied in clinical trials and may be exacerbated by the medication's effects on gastric emptying