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Moreover, the available reports do not allow confident separation of direct drug-related reproductive effects from mediation through weight loss and improvement in insulin resistance
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Disclosures Jerry Meece is a consultant for Astra Zeneca, Eli Lilly, Johnson and Johnson, Novo Nordisk, and Sanofi
Clinical trials have demonstrated substantial weight loss outcomes, with patients losing an average of approximately 15% of their body weight over 68 weeks with semaglutide 2.4 mg weekly in the STEP 1 trial
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