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Muscle weakness
The most dramatic result (mice returning to a body composition indistinguishable from lean age-matched animals) came from combining the inhibitor with a low-fat diet switch, and that study did not include a drug-alone arm
The compound could theoretically interact with medications affecting NAD+ metabolism, energy pathways, or the enzymes responsible for its clearance from the body
Peak results occur during weeks 8 to 12 with consistent use, proper training, and adequate nutrition
New York, NY: Taylor & Francis
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